Table 1.
Number of TGCT cases and controls included for testing associations with SNPs in methylation-related genes by originating study, and for cases by histologic type, family history of TGCT, and history of cryptorchidism
| Studies | TGCT Cases | Controls (N) | ||||
|---|---|---|---|---|---|---|
| ALL (N) | Seminoma histology (N) | Non-seminomatous histology (N) | Family history (N) | Cryptorchidism (N) | ||
| GWAS-DENMARK | 183 | 88 | 55 | na | na | 363 |
| GWAS-NCI | 581 | 243 | 334 | 76 | 131 | 1,056 |
| GWAS-UPENN | 481 | 171 | 299 | 49 | 39 | 919 |
| GWAS- NORWAY/SWEDEN | 1,326 | 766 | 549 | na | na | 6,687 |
| GWAS-UK | 986 | 410 | 410 | 136 | 56 | 4,945 |
| TECAC STUDY | 5,602 | 2,456 | 2,760 | 95 | 295 | 5,006 |
| deCODE ICELAND | 300 | na | na | na | na | 151,991 |
| UK BIOBANK | 697 | 395 | 223 | na | na | 8,716 |
| Total | 10,156 | 4,529 | 4,630 | 356 | 521 | 179,683 |
N: number of subjects
GWAS: genome-wide association study
na: information not available by TECAC study: cases not included in stratified / restricted analysis