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. Author manuscript; available in PMC: 2022 Sep 6.
Published in final edited form as: Mult Scler Relat Disord. 2022 Jun 24;65:103994. doi: 10.1016/j.msard.2022.103994

Figure 3. Forest plots and meta-analysis of the covariate-adjusted regression analyses.

Figure 3.

Area deprivation index in 2015 was the exposure for the median scores of the patient-reported outcomes of neurological and physical function from the latest year between 2018 and 2020. Higher scores of MS symptom burden (MSRS-R), higher scores of gait impairment (PDDS) and lower T-scores of PROMIS-physical function indicated greater neurological and/or physical disability. Each square was the standardized β coefficient, and each line was the 95% confidence interval (95%-CI). The diamond represented the meta-analyzed β coefficient and 95% CI in a random-effects meta-analysis of the two cohorts. Higher ADI was associated with subsequently greater MSRS-R and PDDS. The significance threshold for multiple testing was p=0.0167.