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. 2022 Sep 5;5:910. doi: 10.1038/s42003-022-03839-2

Fig. 7. PSMβ deficiency upregulates serum cytokines in mice at the early phase.

Fig. 7

NMRI mice (n = 8–21/group) were intravenously injected with S. aureus Newman (wild type, WT), or the isogenic mutant strains Δpsmα or Δpsmβ mutants (5 × 106 CFU/mouse) and sacrificed on day 3 or day 10 post-infection. Serum levels of a interleukin 6 (IL-6) and b keratinocyte-derived chemokine (KC) were analyzed. The results from four independent experiments were pooled. The data are reported as mean ± standard error of the mean and analyzed with the Mann-Whitney U test. *P < 0.05; **P < 0.01; ***P < 0.001.