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. 2022 Sep 5;13:5217. doi: 10.1038/s41467-022-32898-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, b Representative coronal sections through the embryonic telencephalon at E11.5 (a) and E16.5 (b) showing expression of Mtg8, Mtg16 and Lhx6. Expression of Mtg16 resembles that of Lhx6, whereas Mtg8 is expressed more widely. MZ, marginal zone; CP, cortical plate; IZ, intermediate zone; SVZ, subventricular zone; VZ, ventricular zone. c–e Expression of Mtg8 (β-gal) at E14.5 (c) and E18.5 (d) in the MGE-derived cortical interneuron lineage (Nkx2-1-Cre;YFP) and quantification (e). Arrows point to Mtg-expressing cells double labelled for YFP. n = 3 embryonic brains at each time-point. f–h Expression of MTG16 at E14.5 (f) and E18.5 (g) in the MGE-derived cortical interneuron lineage (Nkx2-1-Cre;YFP) and quantification (h). Arrow point to Mtg-expressing cell double labelled for YFP. n = 3 embryonic brains at each time-point. All graphs show mean ± SEM. Source data are provided as a Source Data file. Scale bars: (a) 200 μm; (b) 400 μm and higher magnification 100 μm; (c, f) 65 μm; (d, g) 120 μm.