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. 2022 Sep 5;13:5217. doi: 10.1038/s41467-022-32898-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Experimental scheme for overexpression of MTG8 in the MGE lineage by lentiviral transduction of dissociated MGE precursors, followed by transplantation into the cortex of newborn pups. Analysis was carried out in the somatosensory cortex 40 days post transplantation. b Immunohistochemistry and quantification for SST, NPY or PV together with tdTOM and VENUS to detect transplanted and/or transduced MGE precursors differentiating into different interneuron subtypes. A minimum of 300 transplanted cells per experiment were counted. n = 5 independent transplantations for SST and PV, n = 3 independent transplantations for NPY. Two-Way ANOVA was followed by Uncorrected Fisher’s LSD tests. SST P = 0.0147, NPY P = 0.0319, PV P = 0.0166. *P < 0.05. Graph shows mean ± SEM. Source data are provided as a Source Data file. Scale bar 25 μm.