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. 2022 Sep 5;13:5217. doi: 10.1038/s41467-022-32898-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a Immunohistochemistry detecting co-expression of CR/YFP or nNOS/SST/YFP or NPY/SST/YFP in the somatosensory cortex in control animals at P40. Arrowheads point to double-labelled cells for CR/YFP and triple-labelled cells for nNOS/SST/YFP and NPY/SST/YFP. Arrows point to double-labelled SST/YFP cells. b–e Quantification of the above co-expression profiles in control and Mtg8 cKO animals. In the absence of MTG8 there is a significant reduction of SST interneurons co-expressing NPY. All other SST subtypes examined remain unaffected. CR⁺YFP⁺ n = 3 brains per genotype. nNOS⁺SST⁺YFP⁺, NPY⁺SST⁺YFP⁺ and NPY^-SST⁺YFP⁺ n = 4 brains per genotype. Two-tailed unpaired t tests. **P = 0.0064. All graphs show mean ± SEM. Source data are provided as a Source Data file. Scale bar 130 μm.