Table 2.

Discriminatory ability of prediction models for incident type 2 diabetes.

Model		C-statistic (95% CI)
Base modela		0.86 (0.84–0.88)
Enhanced model: base model plus selected metabolic biomarkersb
Total population		0.91 (0.90–0.93)
Population subgroups
BMI	< 25.0 kg/m2	0.91 (0.89–0.93)
	≥ 25.0 kg/m2	0.91 (0.89–0.93)
WC	< 90 cm in men and < 80 cm in women	0.91 (0.88–0.93)
	≥ 90 cm in men and ≥ 80 cm in women	0.92 (0.90–0.94)
Sex	Men	0.91 (0.89–0.94)
	Women	0.92 (0.91–0.94)
Age	< 55 years	0.93 (0.91–0.94)
	≥ 55 years	0.90 (0.88–0.93)

BMI body mass index, WC waist circumference.

^aAge, sex, study area, fasting time, body mass index, family history of diabetes, education, blood pressure, resting heart rate, plasma glucose, triglycerides, statin use.

^bConcentrations of linoleic acid, docosahexaenoic acid, 3-hydroxybutyrate, apolipoprotein A-I, esterified cholesterol, free cholesterol in very small VLDL, glycoprotein acetyls, lactate, phosphatidylcholine, phospholipids in IDL, total cholesterol in very large HDL, total lipids in large HDL, total lipids in small VLDL, triglycerides in large HDL, triglycerides in small HDL, valine, ratios of docosahexaenoic acid to total fatty acids, apolipoprotein B to apolipoprotein A-I, cholesterol esters to total lipids in medium HDL, cholesterol esters to total lipids in small VLDL, free cholesterol to total lipids in large HDL, free cholesterol to total lipids in medium HDL, free cholesterol to total lipids in small HDL, free cholesterol to total lipids in very small VLDL, phospholipids to total lipids in large LDL, phospholipids to total lipids in large VLDL, phospholipids to total lipids in small HDL, triglycerides to total lipids in IDL, triglycerides to total lipids in small VLDL, mean HDL particle diameter.