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. 2022 Sep 5;13:5232. doi: 10.1038/s41467-022-32822-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — FPR1 and selected mutants were expressed in transiently transfected cells. The receptors were stimulated with different concentrations of the indicated agonists, fMIFL (a), WKYMVm (b), AG-14 (c) or Compound 17b (d) plus forskolin for 30 min. Changes in cytoplasmic cAMP concentrations were measured and data were plotted with the maximal cAMP concentrations set as 100%. Data are shown as mean ± SEM of three independent experiments, each in duplicates. Source data are provided as a Source Data file.