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. 2022 Sep 5;5:912. doi: 10.1038/s42003-022-03889-6

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a Changes in body weight after treatment. Tube implantation (OVX + oil only and OVX + high E2) and i.c.v. treatment was performed in OVX female rats at 14 weeks of age. The data are presented as the mean ± SEM (repeated-measures ANOVA) (^*P < 0.05, compared with OVX + oil only and OVX + high E2 groups). b Cumulative food intake for 3 h after i.p. administration of CCK-8 (50 μg/kg body weight) and i.c.v. administration of saline or OXTR-A (150 ng/μl) to the rats in the OVX + oil only group or OVX + high E2 group. The data are presented as the mean ± SEM (two-way ANOVA) (^*P < 0.05, compared with saline i.c.v. and OXTR-A i.c.v. groups).