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. 2022 Aug 23;12:974200. doi: 10.3389/fcimb.2022.974200

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Copyright © 2022 Grajeda, De Chatterjee, Villalobos, Pence, Ellis, Enriquez, Roy, Roychowdhury, Neumann, Almeida, Patterson and Das

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differentially expressed heatmap patterns of potential giardial virulence factors such as arginine deiminase (AD), carbamate kinase (CK), elongation factor (EF), giardin, high cysteine membrane protein (HCMP), ornithine carbamoyltransferase (OCT), tenascin, and variant surface protein (VSP). Each heatmap contains proteins between control (C) and treatments with nystatin (N) (27 μM) and oseltamivir (O) (20 μM) within isolated lipid rafts, large vesicles and small vesicles. Protein samples included have a p-value ≤.05 between normalized data in scaffold and have been transformed to a Z-score for visual simplification.