Table 3.

Diagnostic accuracy characteristics (AUC, sensitivity, specificity and accuracy) for GSH concentrations, susceptibility, and the combined effect of GSH concentration and susceptibility levels to differentiate among the three groups (HO, MCI and Alzheimer’s disease)

Parameter	AUC	S.E.	P-value	Sensitivity	Specificity	PPV	NPV	Accuracy
HO versus MCI
GSH conc.	0.738	0.086	0.017*	0.720	0.692	0.785	0.612	0.709
Susceptibility	0.551	0.104	0.595	0.636	0.688	0.761	0.547	0.656
GSH + susceptibility	0.741	0.085	0.018*	0.692	0.682	0.582	0.776	0.686
HO versus Alzheimer’s disease
GSH conc.	0.868	0.049	0.000*	0.760	0.846	0.799	0.814	0.808
Susceptibility	0.744	0.075	0.006*	0.682	0.682	0.727	0.633	0.682
GSH + Susceptibility	0.856	0.062	0.000*	0.818	0.824	0.789	0.849	0.821
MCI versus Alzheimer’s disease
GSH Conc.	0.675	0.091	0.079	0.615	0.692	0.507	0.777	0.666
Susceptibility	0.722	0.091	0.021*	0.864	0.688	0.843	0.723	0.804
GSH + susceptibility	0.751	0.090	0.020*	0.769	0.765	0.628	0.865	0.766

*All significant values are set to P < 0.05.