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. 2022 Aug 23;10:971992. doi: 10.3389/fcell.2022.971992

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Copyright © 2022 Liu, Liu, Wang, Xie, Liu, Wang, Rong, Xie, Wang, Zeng, Zhou, Peng and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Evaluation of the chemotherapy response and screening of small-molecule drugs. (A) Sensitivity analysis of chemotherapy drugs between the high- and low-risk groups. (B) Volcano plot of DEGs between the high- and low-risk groups. (C–H) Structures of six small-molecule drug candidates, namely, 4-(2-aminoethyl) benzenesulfonamide (C), bongkrek acid (D), esmolol (E), norethisterone (F), parbendazole (G), and RX-821002 (H).