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. 2022 Aug 23;10:971992. doi: 10.3389/fcell.2022.971992

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Copyright © 2022 Liu, Liu, Wang, Xie, Liu, Wang, Rong, Xie, Wang, Zeng, Zhou, Peng and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immune profiles between the two subgroups. (A) Immune cell proportions in COAD patients. (B) Analysis of twenty-two types of tumor-infiltrating immune cells. (C) Boxplot of the differences in the stromal score, immune score, ESTIMATE score, and tumor purity. (D) Comparison of the levels of infiltration of immune cells in the two groups. (E) Differences in MHC molecule expression. (F) Relative abundance of the antitumor immune response between the high- and low-risk groups. (G) Immune checkpoint expression in the high- and low-risk groups. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; ns, not significant.