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. 2022 Aug 23;13:929035. doi: 10.3389/fgene.2022.929035

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Copyright © 2022 Wang, Zhou, Wang, You, Li, Zheng, Zhang, Wang, Kong, Gao and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Further verification of the ability of the m7G-LPS. (A–C) ROC curves of m7G-PLS to predict the sensitivity and specificity of 1-, 3-, and 5-years survival in training (A), testing (B), and ICGC sets (C). (D–F) The time-dependent AUC value with different clinical characteristics in the training, testing, and ICGC set. (G–J) PCA between the high- and low-risk groups based on whole gene expression profiles (G), 29 m7G genes (H), 22 prognostic m7G-related lncRNAs (I), and m7G-LPS (J). m7G, N7-methylguanosine; lncRNAs, long non-coding RNAs; m7G-LPS, m7G-related lncRNA prognostic signature; ROC, Receiver operating characteristic curve.