Safety concept to prevent insulin deficiency of one AID system (Medtronic Minimed 670G). Under the conditions shown on the right, the safety mode “Basal safe” is applied with a low, constant basal insulin delivery over 90 min. In the absence of a response to the visible prompts of the AID system, the transition to the “Manual Mode” of insulin pump therapy takes place. During critical conditions (eg, glucose values >300 mg/dl over 1 hour), this transition to Manual Mode takes place immediately (modified from the User Guide, Medtronic Minimed 670G ).