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In vivo evaluation using collagenase-induced rat tendinopathy model in 4 weeks after injection. (a) Gross images of the injected site. (b) H&E staining images of the tendon (top) and muscle (below). (c) MT staining images of the tendon. Scale bar indicates 40 µm. The mRNA expression levels of (d) inflammation-, (e) apoptosis-, and (f) tendon-related genes in rat tendon. *p < 0.05, **p < 0.01, ***p < 0.001, and #p < 0.0001 indicate statistically significant differences, respectively.
