Table 4.

Clinical and pathological characteristics and TAX1BP1 polymorphism (Genotypes TT: wild homozygote; TA: heterozygote; AA: polymorphic homozygote)

Variables	TT genotype	OR (CI 95%)	TA and AA genotypes	OR (CI 95%)*	p
Tumor sites**
Oral cavity	48	1,00 (ref)	23	2,38 (1,18 – 4,78)	0,01
Pharynx	48	1,00 (ref)	08	0,49 (0,21 – 1,15)	0,10
Larynx	48	1,00 (ref)	11	0,70 (0,32 – 1,52)	0,36
Tumor extension***
T1/T2	46	1,00 (ref)	14	1,12 (0,53 – 2,38)	0,77
T3/T4	89	1,00 (ref)	25	1,09 (0,52 – 2,31)	0,81
Lymph node involvement***
No	74	1,00 (ref)	24	1,00 (ref)
Yes	67	1,00 (ref)	15	0,67 (0,32 – 1,40)	0,28
Stages***
I/II	34	1,00 (ref)	11	1,00 (ref)
III/IV	94	1,00 (ref)	26	0,82 (0,36- 1,87)	0,65

^**Adjusted for age, gender, cigarette smoking and alcoholic beverages drinking.

^**Unknown primary anatomical sites were taken off.

^***Analysis carried out for patients with complete pathology data