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. Author manuscript; available in PMC: 2022 Sep 6.
Published in final edited form as: Clin Trials. 2019 Nov 6;17(1):39–51. doi: 10.1177/1740774519885380

Table 4.

Patients accepting treatment outside of study.

Total Yes No Unknown




No. (Col %) No. (Row %) (Col %) No. (Row %) (Col %) No. (Row %) (Col %)

Total patients not enrolled because of 3584 (−) 1979 (55.2) (−) 1010 (28.2) (−) 595 (16.6) (−)
 Ineligibility 1469 (41.0) 742 (50.5) (37.5) 508 (34.6) (50.3) 219 (14.9) (36.8)
 Site choice 358 (10.0) 265 (74.0) (13.4) 44 (12.3) (4.4) 49 (13.7) (8.2)
 Patient choice 1757 (49.0) 972 (55.3) (49.1) 458 (26.1) (45.3) 327 (18.6) (55.0)
Total reasons patients did not enroll 1886 1 164 (61.7) (−) 454 (24.1) (−) 268 (14.2) (−)
 Research 446 (23.6) 371 (83.2) (31.9) 40 (9.0) (8.8) 35 (7.8) (13.1)
 Work/school 369 (19.6) 244 (66.1) (21.0) 69 (18.7) (15.2) 56 (15.2) (20.9)
 Medication/health 308 (16.3) 193 (62.7) (16.6) 74 (24.0) (16.3) 41 (13.3) (15.3)
 Other reasons 219 (11.6) 148 (67.6) (12.7) 25 (11.4) (5.5) 46 (21.0) (17.2)
 Patient LTBI beliefs 199 (10.6) 14 (7.0) (1.2) 1 60 (80.4) (35.2) 25 (12.6) (9.3)
 Patient lifestyle, family, other 181 (9.6) 1 19 (65.7) (10.2) 31 (17.1) (6.8) 31 (17.1) (11.6)
 Clinic/staff 145 (7.7) 58 (40.0) (5.0) 55 (37.9) (12.1) 32 (22.1) (11.9)
 Communication 19 (1.0) 17 (89.5) (1.5) − (−) (−) 2 (10.5) (0.7)

LTBI = latent tuberculosis infection.