Table 1.
Cholesteatoma clinical features and MMP and TIMP gene expression.
| Patient | Age (years) | Dysacusis | Erosion | MMP-2 | MMP-3 | MMP-13 | TIMP-1 |
|---|---|---|---|---|---|---|---|
| 1 | 12 | Mild conductive | - | - | nt | nt | nt |
| 2 | 27 | Severe mixed | +++ | +++ | - | + | ++ |
| 3 | 46 | Mild conductive | + | +++ | + | - | + |
| 4 | 30 | Severe mixed | + | - | - | - | - |
| 5 | 7 | Moderate conductive | +++ | - | nt | nt | nt |
| 6 | 52 | Severe mixed | ++ | - | nt | nt | nt |
| 7 | 54 | Profound mixed | ++ | - | nt | nt | nt |
| 8 | 58 | Moderate mixed | +++ | - | nt | nt | nt |
| 9 | 17 | Moderate sensorineural | ++ | - | nt | nt | nt |
| 10 | 42 | Moderate conductive | + | + | - | - | - |
| 11 | 45 | Severe mixed | ++ | - | - | - | - |
| 12 | 37 | Moderate conductive | ++ | - | - | - | - |
| 13 | 67 | Severe mixed | +++ | - | - | - | - |
| 14 | 42 | Moderate conductive | + | - | - | - | - |
| 15 | 14 | Moderate conductive | + | - | - | ++ | - |
| 16 | 42 | Moderate conductive | +++ | - | - | - | - |
| 17 | 27 | Mild conductive | ++ | - | nt | ++ | nt |
| 18 | 63 | Severe mixed | ++ | - | nt | nt | nt |
| 19 | 43 | Moderate conductive | ++ | - | nt | + | nt |
nt: not tested.