. 2022 Jun 3;7(3):V. doi: 10.1177/23969873221099736

Table 3.

Baseline characteristics of participants in the studies included in the quantitative analysis performed for PICO 2.

Study	Study design	Treatment	Participants (n)	Women (%)	Aneurysm size range (mm)	Periprocedural stroke
Wiebers et al.^24 a	Observational	No treatment, EVT, MST	4060	76	2–≥25 mm (range)	MST: 286/1917
Wiebers et al.^24 a	Observational	No treatment, EVT, MST	4060	76	2–≥25 mm (range)	EVT: 36/451
Brilstra et al.³⁵	Observational	EVT, MST	51	75	0–>25 (range)	MST: 11/32
Brilstra et al.³⁵	Observational	EVT, MST	51	75	0–>25 (range)	EVT: 3/19
Gallas et al.³⁶	Observational	EVT	302	63	NA^b	EVT: 36/302
Gallas et al.³⁶	Observational	Guglielmi detachable coils	302	63	NA^b	EVT: 36/302
Gentric et al.³⁷	Observational	EVT	107	69	NA^c	EVT: 6/107
Gentric et al.³⁷	Observational	Stent assisted coilling	107	69	NA^c	EVT: 6/107
Hetts et al.³⁸	Observational	EVT	361	77	4–20 (range)	EVT: 22/361
Hetts et al.³⁸	Observational	Stent assisted coil, simple coil	361	77	4–20 (range)	EVT: 22/361
Poncyljusz et al.³⁹	Observational	EVT	78	73	NA	–
Poncyljusz et al.³⁹	Observational	LVIS and LVIS Jr. stents	78	73	NA	–
Darsaut et al.²⁷	RCT	EVT, MST	136	69	3–25 (range)	MST: 3/65
Darsaut et al.²⁷	RCT	EVT, MST	136	69	3–25 (range)	EVT: 7/69
Pumar et al.⁴⁰	Observational	EVT	104	75	<10 mm	EVT: 7/104
Pumar et al.⁴⁰	Observational	SILK flow diverter	104	75	<10 mm	EVT: 7/104
Hanel et al.⁴¹	Observational	EVT	141	88	≤12 mm^d	–
Hanel et al.⁴¹	Observational	Pipeline embolisation device for wide necked aneurysms	141	88	≤12 mm^d	–

EVT: endovascular treatment; MST: microsurgical treatment; NA: not available; RCT: randomised controlled trial.

A small proportion of patients had an associated condition, such as arteriovenous malformation (2.0%) or polycystic kidney disease (1.6%).

Aneurysms <10 mm represented 77% of the participants.

Aneurysms <6 mm represented 52% of the participants.

Aneurysms 7 to 12 mm represented 16% of the participants.