Table 3.
Factors for clinical remission at week 4 after initiation of corticosteroid treatment in outpatients with ulcerative colitis
| Remission (+) (n = 60) | Remission (−) (n = 46) | Univariate analysis | Multivariate analysis | |
|---|---|---|---|---|
| P value | P value | |||
| OR (95% CI) | ||||
| Gender (male) | 20 (33.3%) | 18 (39.3%) | 0.537 | |
| Age, years; median (IQR) | 42 (24–56) | 40 (29–59) | 0.630 | |
| Duration of disease, years; median (range) | 6.27 (2.24–20.9) | 5.91 (1.67–9.24) | 0.167 | |
| Previous use of systemic steroid | 49 (81.7%) | 41 (89.7%) | 0.287 | |
| Previous/present use of thiopurine | 12 (20.0%) | 15 (32.6%) | 0.171 | |
| Partial Mayo score at baseline; median (IQR) | 5 (5–6.25) | 6 (5–7) | 0.035 |
P = 0.015 OR 0.643 (0.451–0.918) |
| Mayo Endoscopic score at baseline; median (IQR) | 2 (1.25–3) | 3 (2–3) | 0.144 | |
| Initial corticosteroid dose | 0.03 |
P = 0.014 OR 3.278 (1.274–8.435) |
||
| <30 mg | 32 (53.3%) | 34 (74.0%) | ||
| ≥30 mg | 28 (46.7%) | 12 (26.0%) | ||
CI, confidence interval; IQR, interquartile range; OR, odds ratio.