Table 2.
CT features of SSNs in the derivation and validation cohorts
| Characteristics | Total (N=681) | Derivation cohort (N=423) | Validation cohort (N=258) | t/Z/χ2 | P value |
|---|---|---|---|---|---|
| Lesion Size (mm) | 11.32 ± 5.00 | 11.33 ± 4.98 | 11.30 ± 5.03 | 0.074a | 0.941 |
| Mean CT value (HU) | -526.16 ± 130.92 | -528.38 ± 131.66 | -522.52 ± 129.88 | -0.566a | 0.571 |
| Volume (cm3) | 0.34 (0.20, 0.82) | 0.34 (0.22, 0.82) | 0.34 (0.19, 0.80) | 0.099b | 0.921 |
| Mass (g) | 0.15 (0.09, 0.34) | 0.15 (0.09, 0.35) | 0.15 (0.08, 0.33) | -0.163b | 0.870 |
| Vascular change | 0.088c | 0.767 | |||
| Present | 246 (36.1%) | 151 (35.7%) | 95 (36.8%) | ||
| Absent | 435 (63.9%) | 272 (64.3%) | 163 (63.2%) | ||
| Bronchiole change | 0.357c | 0.550 | |||
| Present | 132 (19.4%) | 79 (18.7%) | 53 (20.5%) | ||
| Absent | 549 (80.6%) | 344 (81.3%) | 205 (79.5%) | ||
| Lobulation | 0.103c | 0.748 | |||
| Present | 264 (38.8%) | 162 (38.3%) | 102 (39.5%) | ||
| Absent | 417 (61.2%) | 261 (61.7%) | 156 (60.5%) | ||
| Bubble | 0.718c | 0.397 | |||
| Present | 97 (14.2%) | 64 (15.1%) | 33 (12.8%) | ||
| Absent | 584 (85.8%) | 359 (84.9%) | 225 (87.2%) | ||
| Pleural attachment | 0.771c | 0.380 | |||
| Present | 233 (34.2%) | 150 (35.5%) | 83 (32.2%) | ||
| Absent | 448 (65.8%) | 273 (64.5%) | 175 (67.8%) | ||
| Spiculation | 0.051c | 0.822 | |||
| Present | 111 (16.3%) | 70 (16.5%) | 41 (15.9%) | ||
| Absent | 570 (83.7%) | 353 (83.5%) | 217 (84.1%) | ||
| Lesion-lung interface | 0.568c | 0.451 | |||
| Clear | 450 (66.1%) | 275 (65.0%) | 175 (67.8%) | ||
| Blurry | 231 (33.9%) | 148 (35.0%) | 83 (32.2%) |
at value; bZ value; cχ2 value