Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 6;14:126. doi: 10.1186/s13195-022-01068-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 2 — Schematic illustration of the mediation analyses investigating the link between SCD and anxiety/depression scores. Regression coefficients for paths a, b, c, c′, and ab are reported in the figure. The total effect of SCD-Q MyCog on HADS (path c) is shown as the summation of the direct effect adjusted by the given mediator (c′) and the indirect effect (ab). The analyses were adjusted by age, sex, years of education, pre-confinement HADS scores, and time difference between the pre-confinement and confinement assessments. *p < 0.05, **p < 0.01, ***p < 0.001. A The results of the mediation analysis investigating the role of PSS as a mediator between SCD-Q MyCog scores and HADS scores. The indirect effect (path ab) was statistically significant (p = 0.01) corresponding to 63% of the total association between the two variables. B The results of the mediation analysis investigating the role of Aβ as a mediator between SCD-Q MyCog and HADS scores. The indirect effect (path ab) did not show a statistically significant effect (p = 0.45). Abbreviations: SCD-Q, Subjective Cognitive Decline Questionnaire; PSS, Perceived Stress Scale; HADS, Hospital Anxiety and Depression Scale; Aβ, amyloid-beta; CL, Centiloid