Figure 2.

Longitudinal T1-post-contrast MRI demonstrating transition from PsP to true progression for a single subject. (A) Is the post-operative MRI after surgical resection of a left temporo-occipital GBM. The patient was subsequently initiated on a chemoradiation protocol, and the three-month follow-up scan demonstrated new enhancement as shown in (B). This mass was stable on the next follow-up MRI obtained a month later generating a diagnosis of PsP (C). However, there was increased enhancement three months later, accompanied by clinical decline, indicating disease progression (D).