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. 2022 Aug 15;4(1):vdac128. doi: 10.1093/noajnl/vdac128

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© The Author(s) 2022. Published by Oxford University Press, the Society for Neuro-Oncology and the European Association of Neuro-Oncology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Metabolic levels of mI/c-Cr and Lac/Glx within the enhancing volume stratified by clinical status. (A) Box and whisker plots depict that subjects with PsP had higher mean mI/c-Cr and lower Lac/Glx in the enhancing VOI compared to those with true progression. Longitudinal changes in mI/c-Cr and Lac/Glx from PsP to true progression in a single subject are depicted by a black dot connected by a solid line. mI/c-Cr decreased by 56% and Lac/Glx increased by 114% when transitioning from PsP to true progression. The ROC curve for both markers, mI/c-Cr (B), and Lac/Glx (C) is illustrated.