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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Nature. 2022 Mar 23;604(7905):343–348. doi: 10.1038/s41586-022-04533-3

Extended Data Figure 9. mRNA-seq analysis on human fibroblasts.

Extended Data Figure 9.

Cells were infected with Lenti.sup-tRNATyr.EGFP or Lenti.EGFP as control for seven days as described in Fig. 2a. a, Volcano plot showing differentially expressed transcripts in Lenti.sup-tRNATyr.EGFP-treated cells compared to control cells. Red and blue dots denote significantly upregulated and downregulated transcripts (adjusted p<0.01 and fold change>2), respectively. b, Venn diagram showing the upregulated transcripts in a and published set of 1,000 human putative NMD substrates.