Table 3.
Information on the studies and consortia from which genetic association data were obtained
| Exposure | Phenotype name in study | Study | Ancestry | N cases (/controls) | Controls definition/selection criteria | Unit | PMID/link |
|---|---|---|---|---|---|---|---|
| Exposure data | |||||||
| Systolic blood pressure | Systolic blood pressure | Evangelou et al., 2018 | European | 757,601 | - | mmHg | 30,224,653 |
| Outcome data | |||||||
| Pre-eclampsia or eclampsia | Pre-eclampsia or eclampsia | FINNGEN DF6 | European | 4743/136,325 | Women without a hypertensive disorder in pregnancy | Log(OR) (yes vs no) | https://finngen.gitbook.io/documentation |
| Gestational diabetes | Diabetes mellitus in pregnancy | FINNGEN DF6 | European | 7676/130,424 | Women without any pregnancy-related morbidity | Log(OR) (yes vs no) | https://finngen.gitbook.io/documentation |
| Birthweight of first child | First child birthweight | Neale Lab | European | 155,202 | Women who indicated they had given birth to at least one child (based on UKB data-field 2744) |
Birthweight in pounds, split into three ordered categorical variable bins: • 0 for < 7 pounds • 1 for 7 pounds • 2 for > 7 pounds |
http://www.nealelab.is/uk-biobank/ |