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. 2022 Sep 5;22:386. doi: 10.1186/s12903-022-02410-z

Fig. 1.

Fig. 1

Clinical presentation and histopathologic findings of LCH. a Intraoral examination shows multiple ulcers and suppurations on the whole gingival mucosa and left hard-palate, with teeth loss; b Skin biopsy shows the intense proliferation of histiocytes, significant eosinophils and lymphocytes infiltrating (HE, × 600); Positive immunohistochemistry for c CD-1a, d S-100 and e CD163 in oral tissue (IHC, × 200); f Oral condition after one month of treatment HE Hematoxylin and eosin stain; IHC Immunohistochemistry stain