Table 2.
Association between SII and POD with logistic regression models and PSM analysis
| Model | ORa | 95%CI | P |
|---|---|---|---|
| Unadjusted model | 2.709 | 2.373–3.092 | < 0.001 |
| Model 1 (adjusted for preoperative variables)b | 1.615 | 1.384–1.882 | < 0.001 |
| Model 2 (adjusted for intraoperative variables)c | 1.855 | 1.602–2.146 | < 0.001 |
| Model 3 (adjusted all the variables)d | 1.302 | 1.106–1.531 | 0.001 |
| Model PSM (n = 10,062)e | 1.301 | 1.062–1.598 | 0.011 |
SII Systemic-immune-inflammation index, POD Postoperative delirium, OR Odds ratio, CI Confidence interval, PSM Propensity score matching
aThe ORs of SII > 650
bModel 1 adjusted for age, sex, BMI, ASA, alcohol, cerebrovascular disease, COPD, depression and anxiety, antipsychotic drugs, benzodiazepines, hemoglobin, WBC count, albumin, AST, ALT, PT, types of surgery, and anesthesia methods
cModel 2 adjusted for emergency surgery, duration of anesthesia, colloid, blood transfusion, duration of SBP > 140 mmHg, and MAP < 60 mmHg
dModel 3 adjusted for model 1 plus model 2
eModel PSM was a univariate regression model