Table 2.

Comparison of subjective and objective parameters at baseline vs. at 4, 12, and 24 weeks

	Baseline	Week 4	Week 12	Week 24
Total IPSS	17.0 (14.0–21.0)	13.0 (10.3–16.0)***	13.5 (8.8–16.0)***	9.5 (8.8–13.3)***
Q1. Incomplete emptying	2.0 (1.0–3.0)	2.0 (1.0–2.0)*	1.0 (1.0–3.0)	1.0 (0.8–2.3)*
Q2. Daytime frequency	3 (2.3–3.0)	3.0 (2.0–3.0)**	2.0 (2.0–3.0)**	1.0 (1.0–2.0)***
Q3. Intermittency	2.5 (2.0–3.0)	2.0 (1.0–3.0)	1.0 (1.0–3.0)**	1.0 (1.0–2.0)**
Q4. Urgency	2.0 (1.0–3.0)	1.0 (1.0–2.0)**	2.0 (1.0–2.0)*	1.0 (1.0–2.0)*
Q5. Weak stream	3.0 (2.0–4.0)	2.5 (2.0–3.0)**	2.0 (1.8–3.0)***	2.0 (2.0–2.3)**
Q6. Straining	2.0 (1.0–3.0)	1.0 (1.0–2.0)	1.0 (1.0–2.0)*	1.0 (1.0–1.0)*
Q7. Nocturia	2.0 (2.0–3.0)	2.0 (1.0–2.0)**	2.0 (1.0–2.3)**	2.0 (1.0–2.0)*
Voiding symptom subscore	9.0 (8.0–12.0)	8.0 (4.0–10.0)*	7.0 (5.0–9.3)***	5.5 (4.8–7.5)***
Storage symptom subscore	7.0 (6.0–9.0)	5.0 (4.0–8.8)***	5.5 (4.0–7.0)**	4.0 (3.0–5.3)**
QOL score	4.0 (3.0–5.0)	3.0 (2.0–3.8)**	3.0 (2.0–3.0)***	2.0 (2.0–2.5)**
Total OABSS	5.0 (3.0–6.0)	4.5 (3.0–6.0)	4.0 (2.3–6.0)*	3.0 (3.0–4.0)*
SHIM	7.5 (2.3–12.0)	10.5 (4.3–13.5)	10.5 (5.0–16.3)*	11.0 (4.5–16.5)*
NPi	0.4 (0.3–0.5)	0.4 (0.4–0.4)	0.4 (0.3–0.4)	0.3 (0.3–0.4)
Night-time maximum voided volume (mL)	240.0 (157.5–275.0)	270.0 (230.0–300.0)*	300.0 (250.0–340.0)*	290.0 (240.0–310.0)*
Maximum flow rate (mL/s)	9.4 (7.3–13.8)	10.0 (6.3–13.9)	10.6 (5.8–14.0)	11.0 (6.4–12.7)
Residual urine volume (mL)	47.0 (21.0–81.5)	31.5 (17.0–76.8)	44.0 (20.0–93.5)	38.0 (0.0–76.8)

Data are presented as the median (interquartile range)

IPSS, international prostate symptom score; voiding symptom subscore (Q1 + Q3 + Q5 + Q6); storage symptom subscore (Q2 + Q4 + Q7); QOL, quality of life; OABSS, overactive bladder symptom score; SHIM, sexual health inventory for men; NPi, nocturnal polyuria index

^*P < 0.05; **P < 0.01; ***P < 0.001, compared with baseline