Table 3.

Exosomal mRNA as biomarkers in MS

mRNA	Source of exosomes	Function	Refs.
miR-326	Conventional T cells	differentiation and maturation of Th17	[136]
let-7i	Plasma	inhibit the initiation of regulatory T cells	[157]
miR-15b-5p	Serum	Targets FGF-2 implicated in Demyelination and remyelination	[158]
miR-451a	Serum	Regulator of oxidative stress	[158]
miR-30b-5p	Serum	Neuro-axonal injury	[158]
miR-342-3p	Serum	Neuro-axonal injury	[158]
miR-122-5p,miR-196b-5p,miR-301a-3p,miR-532-5b	Serum	Targets STAT3 and AHR, differentiation and regulation of Th17	[159]