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. 2022 Aug 15;61(34):13561–13575. doi: 10.1021/acs.inorgchem.2c02201

Table 2. Activity of Tested Compounds on T. bruceiTC221 and Balb/3T3 Cells.

compound EC50T. brucei TC221 (μM) Balb/3T3 SI
H2L1 0.231 ± 0.008 12.51 ± 1.354 55
H2L2 0.189 ± 0.038 0.465 ± 0.013 2.460
1 0.084 ± 0.005 12.322 ± 0.346 >100
2 0.169 ± 0.038 0.349 ± 0.109 2.065
3 4.347 ± 2.610 32.977 ± 0.347 7.586
4 12.763 ± 4.060 17.163 ± 3.448 1.345
suramin 0.023 ± 0.0008 43.912 ± 1.438 >100