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. 2022 Aug 26;42(7):1897–1911. doi: 10.1148/rg.220045

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© 2022 by the Radiological Society of North America, Inc.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Sclerosing intraductal papilloma and high-grade metastatic carcinoma in a 48-year-old woman who was recalled from routine screening of the right breast for an asymmetry. She received the second dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in the right arm 1 day earlier. In 2020, she underwent left mastectomy for grade 3 invasive ductal carcinoma. (A) Right MLO mammogram shows an asymmetry (arrow) in the superior right breast, 3 cm from the nipple, and an enlarged right axillary lymph node containing several amorphous calcifications (arrowhead). (B) US image of the right breast shows a complex cystic and solid mass (arrow). Biopsy yielded a sclerosing intraductal papilloma. (C) US image of the right axilla shows a suspicious type 5 lymph node with asymmetric cortical thickening of up to 0.6 cm (arrowhead). Biopsy of the lymph node yielded high-grade metastatic carcinoma, consistent with a breast primary. — Sclerosing intraductal papilloma and high-grade metastatic carcinoma in a 48-year-old woman who was recalled from routine screening of the right breast for an asymmetry. She received the second dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in the right arm 1 day earlier. In 2020, she underwent left mastectomy for grade 3 invasive ductal carcinoma. (A) Right MLO mammogram shows an asymmetry (arrow) in the superior right breast, 3 cm from the nipple, and an enlarged right axillary lymph node containing several amorphous calcifications (arrowhead). (B) US image of the right breast shows a complex cystic and solid mass (arrow). Biopsy yielded a sclerosing intraductal papilloma. (C) US image of the right axilla shows a suspicious type 5 lymph node with asymmetric cortical thickening of up to 0.6 cm (arrowhead). Biopsy of the lymph node yielded high-grade metastatic carcinoma, consistent with a breast primary.