FIG. 2.
Various methods used to create cardiac tissue models in vitro. (a) Cell sheet [Reproduced with permission from Masuda et al., Adv. Drug Delivery Rev. 60, 277–285 (2008). Copyright 2008 Elsevier], (b) paper-based model of cardiac ischemia [Reproduced with permission from Mosadegh et al., Adv. Healthcare Mater. 3, 1036–1043 (2014). Copyright 2014, Wiley], (c) organoids [Reproduced with permission from Lewis-Israeli et al., Nat. Commun. 12, 5142 (2021). Copyright 2021 Author(s), licensed under a Creative Commons Attribution (CC BY) License], (d) microfluidic devices [Reproduced with permission from Ellis et al., Small 18, 2201330 (2022). Copyright 2022 Wiley], and (e) bioprinting [Reproduced with permission from Zhang et al., Biomaterials 110, 45 (2016). Copyright 2016 Elsevier].