Table 5.
Annual Average Age-Specific Incidence Ratesa for Childhood Brain and Other Central Nervous System Tumors Ages 0–19 Years by Siteb and Age Groups, CBTRUS Childhood and Adolescent Brain Tumor Report: NPCR and SEER, 2014–2018
| Site | 0–19 years | <1 year | 1–4 years | 5–9 years | 10–14 years | 15–19 years | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total Cases (2014–2018) | Annual Average | Rate (95% CI) | Total Cases (2014–2018) | Annual Average | Rate (95% CI) | Total Cases (2014–2018) | Annual Average | Rate (95% CI) | Total Cases (2014–2018) | Annual Average | Rate (95% CI) | Total Cases (2014–2018) | Annual Average | Rate (95% CI) | Total Cases (2014–2018) | Annual Average | Rate (95% CI) | |
| Frontal, temporal, parietal, and occipital lobes of the brain | 4,128 | 826 | 1.01 (0.98–1.04) | 153 | 31 | 0.78 (0.66–0.92) | 606 | 121 | 0.76 (0.70–0.82) | 712 | 142 | 0.70 (0.65–0.75) | 1,234 | 247 | 1.19 (1.13–1.26) | 1,423 | 285 | 1.35 (1.28–1.42) |
| Frontal lobe | 1,499 | 300 | 0.37 (0.35–0.39) | 49 | 10 | 0.25 (0.19–0.33) | 207 | 41 | 0.26 (0.23–0.30) | 241 | 48 | 0.24 (0.21–0.27) | 450 | 90 | 0.44 (0.40–0.48) | 552 | 110 | 0.52 (0.48–0.57) |
| Temporal lobe | 1,687 | 337 | 0.41 (0.39–0.43) | 59 | 12 | 0.30 (0.23–0.39) | 256 | 51 | 0.32 (0.28–0.36) | 293 | 59 | 0.29 (0.26–0.32) | 507 | 101 | 0.49 (0.45–0.54) | 572 | 114 | 0.54 (0.50–0.59) |
| Parietal lobe | 649 | 130 | 0.16 (0.15–0.17) | 28 | 6 | 0.14 (0.10–0.21) | 115 | 23 | 0.14 (0.12–0.17) | 127 | 25 | 0.12 (0.10–0.15) | 190 | 38 | 0.18 (0.16–0.21) | 189 | 38 | 0.18 (0.15–0.21) |
| Occipital lobe | 293 | 59 | 0.07 (0.06–0.08) | 17 | 3 | 0.09 (0.05–0.14) | 28 | 6 | 0.04 (0.02–0.05) | 51 | 10 | 0.05 (0.04–0.07) | 87 | 17 | 0.08 (0.07–0.10) | 110 | 22 | 0.10 (0.09–0.13) |
| Cerebrum | 1,375 | 275 | 0.34 (0.32–0.35) | 71 | 14 | 0.36 (0.28–0.46) | 260 | 52 | 0.33 (0.29–0.37) | 363 | 73 | 0.36 (0.32–0.40) | 389 | 78 | 0.38 (0.34–0.42) | 292 | 58 | 0.28 (0.25–0.31) |
| Ventricle | 1,333 | 267 | 0.33 (0.31–0.34) | 205 | 41 | 1.05 (0.91–1.20) | 330 | 66 | 0.41 (0.37–0.46) | 241 | 48 | 0.24 (0.21–0.27) | 285 | 57 | 0.28 (0.24–0.31) | 272 | 54 | 0.26 (0.23–0.29) |
| Cerebellum | 3,635 | 727 | 0.89 (0.86–0.92) | 124 | 25 | 0.63 (0.53–0.76) | 980 | 196 | 1.23 (1.16–1.31) | 1,138 | 228 | 1.12 (1.05–1.19) | 803 | 161 | 0.78 (0.72–0.83) | 590 | 118 | 0.56 (0.52–0.61) |
| Brain stem | 2,562 | 512 | 0.63 (0.60–0.65) | 99 | 20 | 0.51 (0.41–0.62) | 642 | 128 | 0.81 (0.75–0.87) | 877 | 175 | 0.86 (0.81–0.92) | 581 | 116 | 0.56 (0.52–0.61) | 363 | 73 | 0.34 (0.31–0.38) |
| Other brain | 2,926 | 585 | 0.71 (0.69–0.74) | 271 | 54 | 1.38 (1.22–1.56) | 663 | 133 | 0.83 (0.77–0.90) | 703 | 141 | 0.69 (0.64–0.74) | 703 | 141 | 0.68 (0.63–0.73) | 586 | 117 | 0.56 (0.51–0.60) |
| Overlapping lesion of brain | 720 | 144 | 0.18 (0.16–0.19) | 62 | 12 | 0.32 (0.24–0.41) | 141 | 28 | 0.18 (0.15–0.21) | 163 | 33 | 0.16 (0.14–0.19) | 190 | 38 | 0.18 (0.16–0.21) | 164 | 33 | 0.16 (0.13–0.18) |
| Brain, NOS | 2,206 | 441 | 0.54 (0.52–0.56) | 209 | 42 | 1.07 (0.93–1.22) | 522 | 104 | 0.66 (0.60–0.71) | 540 | 108 | 0.53 (0.49–0.58) | 513 | 103 | 0.50 (0.45–0.54) | 422 | 84 | 0.40 (0.36–0.44) |
| Spinal cord and cauda equina | 1,330 | 266 | 0.32 (0.31–0.34) | 112 | 22 | 0.57 (0.47–0.69) | 268 | 54 | 0.34 (0.30–0.38) | 222 | 44 | 0.22 (0.19–0.25) | 331 | 66 | 0.32 (0.29–0.36) | 397 | 79 | 0.38 (0.34–0.42) |
| Cranial nerves | 1,859 | 372 | 0.45 (0.43–0.48) | 82 | 16 | 0.42 (0.33–0.52) | 699 | 140 | 0.88 (0.81–0.95) | 448 | 90 | 0.44 (0.40–0.48) | 307 | 61 | 0.30 (0.26–0.33) | 323 | 65 | 0.31 (0.27–0.34) |
| Olfactory nerve | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- |
| Optic nerve | 1,371 | 274 | 0.33 (0.32–0.35) | 73 | 15 | 0.37 (0.29–0.47) | 676 | 135 | 0.85 (0.79–0.92) | 382 | 76 | 0.38 (0.34–0.42) | 157 | 31 | 0.15 (0.13–0.18) | 83 | 17 | 0.08 (0.06–0.10) |
| Acoustic nerve | 288 | 58 | 0.07 (0.06–0.08) | <16 cases | -- | -- | <16 cases | -- | -- | -- | -- | -- | 87 | 17 | 0.08 (0.07–0.10) | 159 | 32 | 0.15 (0.13–0.18) |
| Cranial nerve, NOS | 197 | 39 | 0.05 (0.04–0.06) | <16 cases | -- | -- | 17 | 3 | 0.02 (0.01–0.03) | 33 | 7 | 0.03 (0.02–0.05) | -- | -- | -- | -- | -- | -- |
| Other nervous system | 382 | 76 | 0.09 (0.08–0.10) | 40 | 8 | 0.20 (0.15–0.28) | 135 | 27 | 0.17 (0.14–0.20) | 93 | 19 | 0.09 (0.07–0.11) | 51 | 10 | 0.05 (0.04–0.06) | 63 | 13 | 0.06 (0.05–0.08) |
| Meninges | 738 | 148 | 0.18 (0.17–0.19) | 33 | 7 | 0.17 (0.12–0.24) | 60 | 12 | 0.08 (0.06–0.10) | 94 | 19 | 0.09 (0.07–0.11) | 175 | 35 | 0.17 (0.15–0.20) | 376 | 75 | 0.36 (0.32–0.40) |
| Pituitary and craniopharyngeal duct | 4,508 | 902 | 1.10 (1.07–1.13) | 23 | 5 | 0.12 (0.07–0.18) | 159 | 32 | 0.20 (0.17–0.23) | 603 | 121 | 0.59 (0.55–0.64) | 979 | 196 | 0.95 (0.89–1.01) | 2,744 | 549 | 2.61 (2.51–2.71) |
| Pituitary gland | 3,896 | 779 | 0.95 (0.92–0.98) | -- | -- | -- | -- | -- | -- | 365 | 73 | 0.36 (0.32–0.40) | 821 | 164 | 0.79 (0.74–0.85) | 2,628 | 526 | 2.50 (2.40–2.59) |
| Craniopharyngeal duct | 612 | 122 | 0.15 (0.14–0.16) | <16 cases | -- | -- | -- | -- | -- | 238 | 48 | 0.23 (0.21–0.27) | 158 | 32 | 0.15 (0.13–0.18) | 116 | 23 | 0.11 (0.09–0.13) |
| Pineal gland | 698 | 140 | 0.17 (0.16–0.18) | 22 | 4 | 0.11 (0.07–0.17) | 69 | 14 | 0.09 (0.07–0.11) | 133 | 27 | 0.13 (0.11–0.15) | 229 | 46 | 0.22 (0.19–0.25) | 245 | 49 | 0.23 (0.20–0.26) |
| Olfactory tumors of the nasal cavityc | 23 | 5 | 0.01 (0.00–0.01) | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- | <16 cases | -- | -- |
| Total | 25,497 | 5,099 | 6.23 (6.15–6.30) | 1,235 | 247 | 6.31 (5.96–6.67) | 4,871 | 974 | 6.12 (5.95–6.29) | 5,628 | 1,126 | 5.53 (5.39–5.68) | 6,074 | 1,215 | 5.88 (5.73–6.03) | 7,689 | 1,538 | 7.31 (7.14–7.47) |
aRates are per 100,000.
bThe sites referred to in this table are loosely based on the categories and site codes defined in the SEER site/histology validation list.
cICD-O-3 histology codes 9522–9523 only.
Data are not presented when fewer than 16 cases were reported for the specific category. Average annual counts and associated rates cannot be provided when total cases (2014–2018) are fewer than 16 cases or when a value based on less than 16 cases can be back-calculated using a cell. Suppressed cases are included in the total count.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; CI, confidence interval; CDC, Centers for Disease Control and Prevention; NCI, National Cancer Institute; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology and End Results Program.