FIG. 1.

Accumulation of [³H]dihydrostreptomycin (A) and [³H]gentamicin (B) by E. coli cells resuspended in buffer containing glucose. Cells were incubated with 0.8 μM dihydrostreptomycin or 10 μM gentamicin, and the uptake of drugs by cells of JC7263 (parent) (■) and JZM 320 (ΔacrD mutant) (▴) was examined as described in the text.