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. Author manuscript; available in PMC: 2022 Sep 6.
Published in final edited form as: Ann Oncol. 2021 Dec 16;33(3):288–298. doi: 10.1016/j.annonc.2021.12.002

Figure 3. Overall survival by treatment arm.

Figure 3.

Kaplan-Meier estimates of overall survival by treatment arm for the intent-to-treat population (A) and for patients with sALCL (B). Tick marks indicate censored data. Hazard ratios (A+CHP/CHOP) and 95% CIs were based on a stratified Cox’s proportional hazard regression model with treatment as the explanatory variable. Stratification factors included histologic subtype (ALK+ sALCL versus all other histologies) and baseline IPI score (0–1 versus 2–3 versus 4–5). P values were calculated using a stratified log-rank test. P values are nominal and not adjusted for multiplicity.

A+CHP, brentuximab vedotin, cyclophosphamide, doxorubicin, and prednisone; CHOP, cyclophosphamide, doxorubicin, vincristine, and prednisone; CI, confidence interval; HR, hazard ratio.