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. 2022 Jul 29;323(3):H577–H584. doi: 10.1152/ajpheart.00322.2022

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Copyright © 2022 The Authors

Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.

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Figure 1. — Size distribution of exosome-like extracellular vesicles in reproductive perivascular and nonperivascular adipose tissue from nonpregnant and pregnant rats. A: adipose tissue surrounding uterine arteries (perivascular adipose tissue, utPVAT) and ovaries (periovarian adipose tissue, OVAT) in a gravid rat (gestational age, 16 days, term = 22–23 days). Size distribution of exosome-like extracellular vesicles derived from utPVAT (Exo-utPVAT; nonpregnant, n = 7; pregnant, n = 9; B) and OVAT (Exo-OVAT; nonpregnant, n = 6; pregnant, n = 6; C) of nonpregnant and pregnant rats. Representative graphical displays of intensity particle size distribution (PSD) with logarithmic x-axis and linear y-axis from measurements of vesicles derived from utPVAT (Exo-utPVAT; D) and OVAT (Exo-OVAT; E) from pregnant rats. Values are presented as medians [interquartile ranges, IQR]. A: Student’s t test with Welch’s correction, *P = 0.04. B: Mann–Whitney test, P = 0.31. Exo-OVAT, exosome-like extracellular vesicles derived from periovarian adipose tissue.