Table 5.
Contribution of each oxidative phosphorylation pathway component to the total resistance to energy transfer
| Fuel Transport/Dehydrogenases, % | Electron Transport Chain, % | ATP Production/Transport, % | |
|---|---|---|---|
| G + M | |||
| Control | 16.4 ± 2.2 | 24.5 ± 4.7 | 59.1 ± 5.4 |
| Ischemia | 13.4 ± 1.6 | 25.2 ± 4.6 | 61.4 ± 4.5 |
| P + M | |||
| Control | 19.0 ± 0.9 | 34.0 ± 7.0 | 47.1 ± 7.1 |
| Ischemia | 15.6 ± 5.4 | 28.9 ± 5.5 | 69.9 ± 10.5 |
Values are means ± SE; n = 4–6 rats per condition. Ischemia lowered the activity of every segment of the oxidative phosphorylation pathway but did not alter the percent contribution of each component of the total resistance of the pathway. G, glutamate; M, malate; P, pyruvate. *P < 0.05, significantly different from control, two-tailed t test.