Table 2.
Vehicle | Solubility (mg/mL) |
---|---|
Oil | |
Capryol 90 | 6.41 ± 0.17 |
Capmul MCM | 14.40 ± 0.54 |
Plurol Oleique CC 497 | 10.56 ± 0.33 |
Surfactant | |
Tween 20 | 0.75 ± 0.06 |
Labrasol | 1.09 ± 0.05 |
Cremophor EL | 0.46 ± 0.02 |
Cosurfactant | |
Tetraglycol | 45.11 ± 1.24 |
Transcutol P | 36.54 ± 2.87 |
Brij L4 | 7.74 ± 0.58 |
Values are presented as the mean ± standard deviation (n = 3). INS, insulin; SOS, sodium n-octadecyl sulfate.