Table 10.

Binding interactions of doripenem and diazepam with human potassium channel (PDB ID: 4UUJ) along with their respective bond lengths (Å).

Name of the compound	Binding affinity (kJ/mol)	Hydrogen bonds	Electrostatic bonds	Hydrophobic bonds
				Pi-Alkyl	Alkyl
Doripenem	–9.2	THR 170 (2.16), THR 170 (2.25), LEU 164 (2.61), VAL 155 (2.65), VAL 155 (1.83), VAL 155 (2.32), THR 156 (3.62), THR 158 (3.53), VAL 157 (3.52)	–	–	–
Diazepam	–6.7	ARG 45 (2.50), ARG 45 (3.05), ALA 106 (3.49)	ARG 45 (4.40)	ARG 45 (4.24)	ALA 110 (3.74)