Table 2.
The effect of synergistic inhibition in AML cell lines.
| MV4-11 | |||||
| Concentration | 24 h | 48 h | |||
| Apa | HHT | Fa | CI | Fa | CI |
|
| |||||
| 2.5 | 2 | 0.14 | 0.1927 | 0.36 | 0.1244 |
| 5 | 4 | 0.18 | 0.2579 | 0.38 | 0.2191 |
| 10 | 8 | 0.19 | 0.4723 | 0.50 | 0.2153 |
| 20 | 16 | 0.39 | 0.2584 | 0.72 | 0.1136 |
|
| |||||
| MOLM-13 | |||||
| Concentration | 24 h | 48 h | |||
| Apa | HHT | Fa | CI | Fa | CI |
|
| |||||
| 2.5 | 2 | 0.12 | 0.5103 | 0.14 | 0.5988 |
| 5 | 4 | 0.17 | 0.3835 | 0.22 | 0.5731 |
| 10 | 8 | 0.20 | 0.5256 | 0.49 | 0.2373 |
| 20 | 16 | 0.38 | 0.2088 | 0.75 | 0.1181 |
|
| |||||
| OCI-AML2 | |||||
| Concentration | 24 h | 48 h | |||
| Apa | HHT | Fa | CI | Fa | CI |
|
| |||||
| 2.5 | 2 | 0.18 | 0.1715 | 0.08 | 0.9547 |
| 5 | 4 | 0.24 | 0.128 | 0.20 | 0.4447 |
| 10 | 8 | 0.25 | 0.2212 | 0.50 | 0.1198 |
| 20 | 16 | 0.39 | 0.0764 | 0.71 | 0.0660 |
|
| |||||
| OCI-AML3 | |||||
| Concentration | 24 h | 48 h | |||
| Apa | HHT | Fa | CI | Fa | CI |
|
| |||||
| 2.5 | 2 | 0.07 | 0.5814 | 0.28 | 0.080 |
| 5 | 4 | 0.14 | 0.3159 | 0.35 | 0.0563 |
| 10 | 8 | 0.28 | 0.1578 | 0.42 | 0.0435 |
| 20 | 16 | 0.37 | 0.1682 | 0.57 | 0.0126 |
Fa: fraction affected.