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. 2022 Aug 30;2022:3553617. doi: 10.1155/2022/3553617

Table 2.

Bioactive molecules transferred via exosomes in different cell or animal models of oxidative stress.

Exosomes OS7 models in vivo/in vitro Measurement of OS Bioactivate ingredients Ref.
Huc-MSC-exos IRI2/H2O2 SOD1, MDA, ROS MnSOD [32]
BM-MSC-exos AβOs ROS Catalase [31]
CPCs-exos Doxorubicin and trastuzumab ROS SOD, miR-146a-5p [43]
Exosomes from young cells Young cell model ROS GSTM2 [44]
Huc-MSC-exos CCl4/CCl4 or H2O2 ROS, 8-OHdG, MDA GPX1 [40]
BM-MSC-exos H2O2 ROS Mitochondrial proteins [42]
Huc-MSC-exos Seizure/H2O2 CAT, SOD, GSH-Px, FRAP, TOM20, FIS1, COX IV, iNOS, HMGB1, HO-1, Nrf2, 8-OHdG,4-HNE, DT miR-215-5p, miR-424-5p, miR-31-3P, miR-193b-3p, and miR-200b-3p [10]
Huc-MSC-exos AMI GSH, ROS, MDA miR-23a-3p [48]
BM-MSC-exos IS5 ROS miR-132-3p [51]
Hamsc-exos POI/POI ROS miR-320a [47]
BM-MSC-exos H2O2 SOD, ROS, MDA miR-214 [49]
ASC-exos UVB ROS miR-10a-5p [50]
Exosomes from astrocyte Oxygen and glucose deprivation SOD, GSH-Px,CAT, MDA miR-29a [52]
M1-exos ROS miR-155 [60]
Exosomes from vascular adventitial fibroblasts of normal rats Primary VSMCs derived from SHR ROS, NOX activity, NOX2 miR-155-5p [46]
Exosomes from CMs ROS, MDA, SOD circHIPK3 [54]

1SOD expression; 2ischemia-reperfusion injury; 3acute kidney injury; 4unilateral ureteral obstruction; 5ischemic stroke; 6traumatic acute lung injury; 7oxidative stress.