| (i) MSM or transgender women who engage in unprotected anal sex, particularly receptive anal sex |
| (ii) MSM or transgender women with multiple anal sex partners |
| (iii) MSM or transgender women with syphilis or rectal STIs |
| (iv) Individuals with one or more HIV-positive sex partners who have detectable viral loads or are not taking ART |
| (v) Individuals who have been prescribed one or more courses of nonoccupational postexposure prophylaxis (nPEP) with ongoing high-risk behavior |
| (vi) Serodiscordant couples who want a safer conception strategy |
| (vii) Injection drug users |
| (viii) Commercial sex workers or individuals who engage in transactional sex |
| (ix) Individuals who use stimulant drugs, such as methamphetamine, while engaging in high-risk sexual behaviors |
| (x) Individuals who request PrEP |
