Table 1.

Characteristics of included studies.

Source	Country	Data collection period	Sample size	Study subjects’ age (in years)	Response rate (reported by authors)	Sampling strategy	Sampling unit	AD definition
Choi34	South-Korea	2008	6453	0–6	70–79	Convenience	School	ISAAC
Cibella61	Italy	2005–2006	2150	10–17	80 +	Unclear	School	Modified ISAAC
Duhme49	Germany	1994–1995	13,123	5–8; 12–15	80 +	Random	School	ISAAC
Emerson54	UK	1995–1996	1761	1–5	80 +	Convenience	General practice	UK
Flohr76	France, Greece, Italy, Netherlands, Norway, Spain, UK, Latvia, New Zealand	1998–2004	20,049	8–12	NR	Random	School	ISAAC
Flohr75	Greece, Norway, Spain, Latvia, Iceland, New Zealand	1998–2004	11,241	8–12	NR	Random	School	ISAAC
Flohr74	France, Greece, Netherlands, Norway, Spain, Latvia, Estonia, New Zealand	1998–2004	11,587	8–12	NR	Random	School	ISAAC
Garcia-Marcos77	Estonia, Hungary, Lithuania, Poland, New Zealand, Belgium, Portugal, Spain, Japan, Canada, USA, Finland	2001–2003	142,085	6–7; 13–14	NR	Random	School	ISAAC
Anderson55	UK	1995, 2002	30,838	12–14	80 +	Random	School	ISAAC
Grize 200673	Switzerland	1992, 1995, 1998, 2001	5446	5–7	70 +	Convenience	School	ISAAC
Guiote-Domínguez71	Spain	2005	381	6–7; 13–14	NR	Random	School	ISAAC
Hong35	South-Korea	2008	10,383	0–13	NR	Convenience	School	ISAAC
Kudzyte66	Lithuania	1994–1995	1879	6–7	80 +	random	school	ISAAC
Kurosaka42	Japan	2005–2006	11,116	6	80 +	Convenience	School	ISAAC
Lee36	South-Korea	2005	8631	0–19	NR	Random	Individual	Self-report of physician diagnosis
Augustin50	Germany	2009	293,181	0–18	NA	Random	Health insurance data	ICD-10
Miyake43	Japan	2004–2005	23,338	6–15	NR	Random	School	ISAAC
Miyake44	Japan	2001	5539	12–15	NR	Random	School	ISAAC
Mortz57	Denmark	1995–1996	1501	12–16	NR	Random	School	Hanifin & Rajka
Radtke 201451	Germany	2009	1,349,671	18–100	NA	Random	Health insurance data	ICD-10
Sasaki45	Japan	2012	28,343	6–12	NR	Unclear	Individual	ISAAC
Saunes70	Norway	1995–1997	8393	13–19	80 +	Random	Individual	ISAAC
Silverberg59	USA	2005–2006	4970	20-	70–79	Random	Individual	Modified ISAAC
Ukawa46	Japan	unclear	4254	6–12	< 70	Convenience	School	ISAAC
Kim72	Sweden	2000, 2008	17,946	15	< 70	Random	Individual	ISAAC
Asher67	New Zealand	1992–1993	31,083	6–7; 13–14	80 +	Random	School	ISAAC
Asher78	UK, Spain, Canada	2002–2003	67,414	6–7; 13–14	NR	Random	School	ISAAC
Kolokotroni64	Cypros	1999–2000; 2007–2008	7160	7–8	80 +	Random	School	ISAAC
Austin56	UK	1995	27,507	12; 13; 14	80 +	Random	School	ISAAC
Lee37	South-Korea	2008	8644	6–11; 12–14	80 +	Random	School	Modified ISAAC
Lee38	South-Korea	2012–2013	1820	6–12; 12–15; 15–18	NR	Random	School	Modified ISAAC
Banac63	Croatia	2001–2002, 2009–2010	6060	6–7; 13–14	80 + ; 70–79	Random	School	ISAAC
Oh41	South-Korea	1995; 2000	82,631	6–12; 12–15	80 +	Random	School	ISAAC
Remes65	Finland	1994–1995	11,607	13–14	80 +	Random	School	ISAAC
Silverberg60	USA	2005–2006	3049	8–11; 12–15; 16–19	80 +	Random	Individual	Modified ISAAC
Sugiyama47	Japan	1995–1996	4466	13–14	NR	Unclear	School	ISAAC
Sybilski68	Poland	2006–2008	18,617	6–7; 12–14; 20–44	< 70	Random	Individual	ISAAC
van de Ven69	Netherlands	2003	9713	12; 13; 14	80 +	Random	School	modified ISAAC
Wang62	Canada	2003	8334	13–14	NR	Random	School	ISAAC
Yura48	Japan	1993–2006	2,802,403	7–12	80 +	Random	School	Self-report of physician diagnosis
Zutavern52	Germany	1995–1996	11,904	5–11	70–79	Random	School	modified ISAAC
Worm53	Germany	1998–2000	1739	18–65	< 70	Random	Individual	Hanifin & Rajka
Vinding58	Denmark	2010–2013	16,507	30–39; 40–49; 50–59; 60–69; 70–79; 80–89	< 70	Random	Individual	Self-report by modified UK diagnostic criteria
Park39	South-Korea	2005	1989	20–39; 40–59; 60-	NR	Random	Individual	Self-report of physician diagnosis
Yu40	South-Korea	2003–2008	NA	< 2; 2–5, 6–18	NA	Random	Health insurance data	ICD-10

AD—atopic dermatitis; NR—not reported; NA—not applicable; ISAAC—criteria of the International Study of Asthma and Allergies in Childhood; Hanifin & Rajka—self-reported score of symptoms based on the Hanifin and Rajka criteria; UK—physician’s diagnosis based on UK refinement of diagnostic criteria; ICD-10—physician’s diagnosis according to ICD-10.