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. Author manuscript; available in PMC: 2022 Sep 7.
Published in final edited form as: Nat Rev Cardiol. 2019 Aug 12;17(3):137–144. doi: 10.1038/s41569-019-0247-5

Table 1 ∣.

Regression model of risk factors for cardiovascular disease

Risk factor HR (95% CI)
Age 50–59 years 2.20 (1.32–3.69)
Age 60–69 years 2.41 (1.44–4.02)
Age ≥70 years 6.27 (3.77–10.42)
Female sex 0.68 (0.50–0.93)
Has type 2 diabetes mellitus 2.18 (1.62–2.94)
Former or current smoker 1.40 (1.04–1.90)
Hypertension stage II–IV 1.20 (0.89–1.62)
Total-cholesterol level >200 mg/dl 1.40 (1.04–1.88)
HDL-cholesterol level <35 mg/dl 1.46 (0.98–2.18)
HDL-cholesterol level >60 mg/dl 0.77 (0.52–1.13)
CHIP present 1.82 (1.15–2.89)

Hazard ratios and 95% confidence intervals associated with Framingham risk factors and CHIP in longitudinal population-based cohorts. Data obtained from a Cox regression using 3,661 individuals from Jackson Heart Study, Framingham Heart Study and Finland–United States Investigation of NIDDM Genetics in REF.15. CHIP, clonal haematopoiesis of indeterminate potential; NIDDM, non-insulin-dependent diabetes mellitus.