Table 1 ∣.
Risk factor | HR (95% CI) |
---|---|
Age 50–59 years | 2.20 (1.32–3.69) |
Age 60–69 years | 2.41 (1.44–4.02) |
Age ≥70 years | 6.27 (3.77–10.42) |
Female sex | 0.68 (0.50–0.93) |
Has type 2 diabetes mellitus | 2.18 (1.62–2.94) |
Former or current smoker | 1.40 (1.04–1.90) |
Hypertension stage II–IV | 1.20 (0.89–1.62) |
Total-cholesterol level >200 mg/dl | 1.40 (1.04–1.88) |
HDL-cholesterol level <35 mg/dl | 1.46 (0.98–2.18) |
HDL-cholesterol level >60 mg/dl | 0.77 (0.52–1.13) |
CHIP present | 1.82 (1.15–2.89) |
Hazard ratios and 95% confidence intervals associated with Framingham risk factors and CHIP in longitudinal population-based cohorts. Data obtained from a Cox regression using 3,661 individuals from Jackson Heart Study, Framingham Heart Study and Finland–United States Investigation of NIDDM Genetics in REF.15. CHIP, clonal haematopoiesis of indeterminate potential; NIDDM, non-insulin-dependent diabetes mellitus.