TABLE 3.
Linear regression analyses of the gene expression of OPN splice variants and integrins with the Breslow thickness of primary melanomas.
| Osteopontin isoforms | β | 95% CI | p-value |
|---|---|---|---|
| OPNa | 0.115 | −0.011–0.242 | 0.071 |
| OPNb | 0.172 | −0.069–0.414 | 0.155 |
| OPNc | 0.217 | 0.112–0.322 | <0.001 |
| OPN4 | −0.762 | −1.343–(−0.181) | 0.012 |
| OPN5 | −3.030 | −8.237–2,176 | 0.242 |
| Integrins | β | 95% CI | p-value |
| ITGA2 | −23.061 | −30.158–(−15.964) | <0.001 |
| ITGA3 | −2.338 | −6.861–2.185 | 0.296 |
| ITGA5 | 2.697 | 0.956–4.438 | 0.004 |
| ITGA6 | −9.079 | −20.317–2.158 | 0.108 |
| ITGA9 | −14.345 | −41.876–13.185 | 0.292 |
| ITGAV | −15.465 | −30.958–0.046 | 0.051 |
| ITGB1 | −5.086 | −13.612–3.440 | 0.229 |
| ITGB3 | 0.023 | −0.099–0.146 | 0.7 |
β is a regression coefficients which indicates the direction and size of effect between variables. CI: confidence interval. Bold values indicates significant associations.