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. 2022 Aug 24;13:932154. doi: 10.3389/fphar.2022.932154

TABLE 2.

The effective dosages and therapeutic durations of G6PD inhibitors in animal models of cancer.

Inhibitors Organism Dose Duration Injection type References
6-An Mouse 4 mg/kg/3d - Intraperitoneal injection Sun et al., (2021b)
Mouse 23 mg/kg/d - Intraperitoneal injection Zhang et al., (2020)
Mouse 20 mg/kg/10d 40d Intraperitoneal injection Best et al., (2019)
Mouse 5 mg/kg/day 23d Intraperitoneal injection Poulain et al., (2017)
DHEA Mouse 80 mg/kg/3d 20d Intraperitoneal injection Wang et al., (2020)
NEOU Mouse 1.5 mg/kg/d 21d Intraperitoneal injection Kitagawa et al., (2021)
Mouse 1.5 mg/kg/d 28d Intraperitoneal injection Joshi et al., (2020)
Epi Rats 30 mg/kg/d 28d Intraperitoneal injection Dhagia et al., (2021)
Polydatin Mouse 5 mg/kg/d 14d Intraperitoneal injection Su et al., (2021)
Mouse 100 mg/kg - Intraperitoneal injection Mele et al., (2018)