TABLE 2.
Differentially methylated regions (DMRs) shared by the mothers and their children.
| GenId Chr | Cluster Length (N of CpG) | N signif Probes within cluster | Methylation N > C Mother/Child | Genomic coordinates (GRCh37/hg19) | Regulatory Feature Group* | Genomic location (UCSC RefGene)* |
|---|---|---|---|---|---|---|
| PM20D1 Chr1 | 14 | 13 | −/+ | Start 205818668 N-shore End 205819609 S-shore | CpG island; Promoter; DNaseI hypersensiti-vity | Body TSS1500 |
| DUSP22 Chr 6 | 14 | 12 | +/+ | Starts 291634 N-shore 293331 S-shore | Promoter_Associated | Body TSS1500 |
| SLC17A3 Chr 6 | 8 | 7 | +/+ | Start 25882590 S_Shore End 25882328 Island | Unclassified_Cell_type_ specific | Pseudo gene (HIST1H2APS2) |
| ZFP57 Chr 6 | 23 | 22 | −/− | Start 29648161 Ends 29649084 | Overlaps enhancer and promoter marks Cell_type_specific | Flanking Tss; Body |
| PON1 Chr 7 | 11 | 9 | −/+ | Start 94953653 N-shore End 94954438 S-shore | CpG island; promoter | Body TSS1500 |
| FGFR2 Chr 10 | 24 | 12 | −/− | Start 123355239 N-shore End 123356514 N-shore | Overlaps enhancer marks; TF binding; DNaseI hypersensitivity mark | TSS1500; 5′UTR |
| WNK4 Chr 17 | 14 | 14 | +/+ | Start 40935998 CpG Island End 40937908 S-shore | CpG island; DNaseI hypersensitivity mark | Body |
| URKC Chr 19 | 14 | 13 | +/+ | Start 557741934 N-shore End 57742444 Island | — | TSS1500 5′UTR; 1stExon |
| ZADH2 Chr 18 | 12 | 11 | −/− | Start; 72916012 N_Shore End 72917390 S_Shore | Promoter_Associated_Cell type_specific; CpG island; DNaseI hypersensitivity mark | Body Body; 5′UTR; 1stExon |
Note: (*) Information presented in “Regulatory Feature” and “Genomic location with respect to assigned gene (UCSC_ RefGene)” columns was retrieved from Illumina Manifest (https://we.tl/t-23Rrw2Lr5l) and completed using annotations from UCSC Genome Browser on Human (Illumina Inc., san diego, United States) and HaploReg V4.1 (Ward and Kellis, 2012).