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. 2022 Aug 24;13:966740. doi: 10.3389/fphys.2022.966740

TABLE 2.

Differentially methylated regions (DMRs) shared by the mothers and their children.

GenId Chr Cluster Length (N of CpG) N signif Probes within cluster Methylation N > C Mother/Child Genomic coordinates (GRCh37/hg19) Regulatory Feature Group* Genomic location (UCSC RefGene)*
PM20D1 Chr1 14 13 −/+ Start 205818668 N-shore End 205819609 S-shore CpG island; Promoter; DNaseI hypersensiti-vity Body TSS1500
DUSP22 Chr 6 14 12 +/+ Starts 291634 N-shore 293331 S-shore Promoter_Associated Body TSS1500
SLC17A3 Chr 6 8 7 +/+ Start 25882590 S_Shore End 25882328 Island Unclassified_Cell_type_ specific Pseudo gene (HIST1H2APS2)
ZFP57 Chr 6 23 22 −/− Start 29648161 Ends 29649084 Overlaps enhancer and promoter marks Cell_type_specific Flanking Tss; Body
PON1 Chr 7 11 9 −/+ Start 94953653 N-shore End 94954438 S-shore CpG island; promoter Body TSS1500
FGFR2 Chr 10 24 12 −/− Start 123355239 N-shore End 123356514 N-shore Overlaps enhancer marks; TF binding; DNaseI hypersensitivity mark TSS1500; 5′UTR
WNK4 Chr 17 14 14 +/+ Start 40935998 CpG Island End 40937908 S-shore CpG island; DNaseI hypersensitivity mark Body
URKC Chr 19 14 13 +/+ Start 557741934 N-shore End 57742444 Island — TSS1500 5′UTR; 1stExon
ZADH2 Chr 18 12 11 −/− Start; 72916012 N_Shore End 72917390 S_Shore Promoter_Associated_Cell type_specific; CpG island; DNaseI hypersensitivity mark Body Body; 5′UTR; 1stExon

Note: (*) Information presented in “Regulatory Feature” and “Genomic location with respect to assigned gene (UCSC_ RefGene)” columns was retrieved from Illumina Manifest (https://we.tl/t-23Rrw2Lr5l) and completed using annotations from UCSC Genome Browser on Human (Illumina Inc., san diego, United States) and HaploReg V4.1 (Ward and Kellis, 2012).