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. 2022 Aug 24;13:912202. doi: 10.3389/fphar.2022.912202

TABLE 3.

The association between pharmacokinetic parameters of vancomycin and vancomycin-induced AKI.

Pharmacokinetic p-value
Baseline serum creatinine 0.024
Baseline GFR a 0.009
Trough concentration 1 (0h) 0.020
Peak concentration (1h) 0.020
Trough concentration 2 (12h) 0.017
AUCτ 0.015
AUC24h 0.015
Vd 0.032
Cl 0.028
k 0.138
t ½ 0.259
a

Glomerular filtration rate.